http://amigo.geneontology.org/amigo/term/GO:0060271 WebOct 15, 2024 · The Primary Cilium and Primary Ciliogenesis. (A) Transmission electron micrograph of the primary cilium protruding from the basal body at the cell surface of a human retinal pigment epithelial cell (hTERT-RPE1), Scale bar, 250 nm. (B) Schematic representation of a cross-section of the axoneme of a cilium. (C) Schematic …
(PDF) Cilium structure, assembly, and disassembly regulated by the ...
WebAug 22, 2024 · The primary cilium is a hair-like, microtubule-based organelle that is covered by the cell membrane and extends from the surface of most vertebrate cells. It detects and translates extracellular signals to direct various cellular signaling pathways to maintain homeostasis. It is mainly distributed in the proximal and distal tubules and collecting … WebJun 28, 2016 · The primary cilium is an antenna-like, immotile organelle present on most types of mammalian cells, which interprets extracellular signals that regulate growth and … fischer rcs sprint crown jr
Cilium assembly and disassembly - PubMed
WebJun 1, 2016 · Cilium assembly proceeds through a series of orchestrated and well-defined stages (labelled I–IV), resulting in the dramatic remodelling of the maternal centriole. Exit from the cell cycle initiates the recruitment of Rabin8, a guanine nucleotide exchange factor (GEF), to the pericentriolar recycling endosome, whereupon it is activated by ... WebFeb 15, 2010 · The commitment of a cell to primary cilium assembly is first reflected by the differentiation of the mother centriole into a basal body . Centrioles are short (0.4 μm length) barrels of nine triplet microtubules, and each cell in the G1 phase contains one centriole that was assembled during the previous division (daughter centriole) and one ... Webcilium organization; microtubule-based flagellum assembly; Definition: The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell … fischer rc trend test