Cisplatin ic50
WebThe 50 % inhibitory concentration (IC50) of cisplatin in A549 and A549/DDP cells 48 h after drug treatment Source publication +4 RNA interferences targeting the Fanconi … WebSep 1, 2015 · Cisplatin, an alkylating agent has been successfully used since decades for the treatment of variety of cancers viz. bone cancer, lung cancer, head and neck cancer, …
Cisplatin ic50
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WebDrug: Cisplatin - Cancerrxgene - Genomics of Drug Sensitivity in Cancer Genomics of Drug Sensitivity in Cancer Compound: Cisplatin Drug Target: DNA crosslinker Drug Target … STR profiles of cell lines Cell line authentication. Concerns around the … The IC50 and AUC are estimated using a non-linear mixed effect model fitting a … Users have a non-exclusive, non-transferable right to use data files for … WebFor comparison, cisplatin, a common clinical drug for bladder cancer, showed IC 50 values of 1.33 and 4.98 µg/mL for T24 and J82 cells at 48 h CCK-8 assay, respectively [27]. Cisplatin also...
WebJun 5, 2024 · We first analyzed the correlation between TFEB expression and half maximal inhibitory concentration (IC50) of CDDP using Genomics of Drug Sensitivity in Cancer … WebAfter an incubation with DDP/EXOs, the cell lines exhibited a higher IC50 value for cisplatin, P-gp expression, migration and invasion capabilities and a lower apoptosis …
WebBioAssay record AID 625684 submitted by ChEMBL: Ratio of cisplatin IC50 to compound IC50 for mouse B16F10. WebAug 27, 2024 · The combination of sodium butyrate with cisplatin decreased the IC50 value of cisplatin and attenuated the cytotoxic effect of cisplatin on the normal cells. Accordingly, we selected SGC-7901 cells and HGC-27 cells, which showed better sensitivities to sodium butyrate to perform the subsequent experiments.
WebCombination therapy of cisplatin and resveratrol to induce cellular aging in gastric cancer cells: Focusing on oxidative stress, and cell cycle arrest . × Close Log In. Log in with Facebook Log in with Google. or. Email. Password. Remember me on this computer. or reset password. Enter the email address you signed up with and we'll email you a ...
WebApr 10, 2024 · The half-maximal inhibitory concentration values (IC 50) were calculated by interpolation from the nonlinear regression curves obtained from cell proliferation/cytotoxicity data using “log (inhibitor) versus the normalized response–variable slope equation”. A p -value lower than 0.05 was considered statistically significant. 3. Results how many sailors died on the bismarckWebThe IC50 values of the two platinum derivatives varied considerably. The values for cisplatin varied between 0.022 microgram ml-1 and 0.56 microgram ml-1 and the … how many sailors died on the moskvaWebThe SIN mean IC50 for HGC-27, SGC-7901, and BGC-803 at 24 hours was 372.60, 284.40, and 279.70 μM; The cisplatin mean IC50 for HGC-27, SGC-7901, and BGC-803 at 24 hours was 3.85, 3.13, and... how many sails in raftWebOverexpressing miR-515-5p markedly reduced cisplatin and 5-Fu IC50 values in HK-1/CDDP and CNE-1/CDDP cells, while IL-25 transfection was sufficient to reverse this phenotype (Figure 4E and F). As such, our data demonstrate that circNRIP1 enhances 5-Fu and cisplatin resistance in NPC cells at least in part via sequestering miR-515-5p and ... how did ancient egyptians writehow many sailors on a ddgWebIC 50 values for cisplatin, curcuminoid, and combination treatments in A549 cell culture. Standard deviation values are provided after the ± symbol for each inhibitory … how did ancient greece contribute to scienceWebA cisplatin-resistant cell subline, HeLa/CDDP cells, showed a 19-fold resistance to cisplatin compared with the parent cells. The subline showed a collateral sensitivity to … how did ancient egyptians use mathematics