Web29. júl 2011 · Phf17 is the second most significant novel candidate in the list. It is located on mouse chromosome 3 and it is not near any of the known imprinting cluster. Phf17 (also known as Jade1) is a component of the HBO1 complex, which has a histone H4-specific acetyltransferase activity and performs most of the histone H4 acetylation in vivo (Foy et ... A small family of proteins named Gene for Apoptosis and Differentiation (JADE) includes three members encoded by individual genes: Plant Homeo-domain-17 (PHF17, JADE1), PHF16 (JADE3), and PHF15 (JADE2). All JADE family proteins bear two notable mid molecule domains: the canonical Plant … Zobraziť viac JADE1 is a protein that in humans is encoded by the JADE1 gene. Zobraziť viac Nagase et al. cloned and sequenced 100 individual cDNAs from fetal brain cDNA library, including clone KIAA1807 which was designated PHF17. The predicted 702-amino acid protein product of that clone was similar to the human zinc finger protein BR140 … Zobraziť viac JADE1 proteins are multifunctional and interact with several protein partners. Histone acetylation Function of JADE1 in histone acetylation and transcription … Zobraziť viac Role of JADE1 in human disease has not been elucidated. A recent study searched for novel submicroscopic genetic changes in myelofibrosis, which is a bone marrow cancer. The study identified seven novel deletions and translocations in small cohort of … Zobraziť viac The full length JADE1 polypeptide bears one canonical and one extended PHD zinc finger domains. Other domains include the N-terminal candidate PEST domain, Enhancer of polycomb-like domain and the C-terminal nuclear localization (NLS) signal … Zobraziť viac The biological role of JADE1 has not been elucidated. Limited number of publications addresses this question using mice models. The most comprehensive study which was … Zobraziť viac Several proteins interact with JADE1, including: pVHL, TIP60, HBO1, ING4, ING5, β-catenin, NPHP4. Zobraziť viac
A survey for novel imprinted genes in the mouse placenta by …
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Anti-PHF17 (AB2) antibody produced in rabbit
Web9. apr 2024 · Innovate through Integrated Solutions Home; Contact Us; English Deutsch; 日本語; 简体中文; Products. Product Browser; Product Discounts & Benefits WebPHF17 (PHD finger protein 17) is a short-lived, kidney-enriched Jade protein consisting of canonical plant homeodomain (PHD) finger protein and a non-canonical extended PHD with zinc-binding ability. It is localized in the nucleus and is highly expressed in the kidney and renal proximal tubule cells. WebPHF17 (PHD finger protein 17) is a short-lived, kidney-enriched Jade protein consisting of canonical plant homeodomain (PHD) finger protein and a non-canonical extended PHD … discord how to customize playing