Purple hand syndrome phenytoin
WebSep 1, 2003 · Sixty-one doses of phenytoin were administered in the PICU, 38 in the four medical and one surgical wards, and one in the A & E department. In 88 exposures, the i.v. cannula was placed in the upper limb (antecubital fossa or dorsum of the hand); in 12 the cannula was inserted in the lower limb (dorsum of foot or femoral vein within the groin). WebRarer cutaneous side effects include drug-induced lupus, purple hand syndrome, pigmentary alterations and IgA bullous dermatosis. Phenytoin can effect clotting function and alter …
Purple hand syndrome phenytoin
Did you know?
WebApr 1, 2016 · A therapeutic phenytoin level of 15.3 mcg/mL (albumin 3.6 g/dL) on day 9 of phenytoin therapy proved consistency with patient reports of medication compliance. After 5 days of warfarin 10 mg and continued dose increases, the INR increased from 0.98 to 1.49. On day 13, the patient developed tingling, numbness and blue discoloration in the hands. WebOct 1, 1998 · Objective: To determine the incidence, risk factors, and long-term sequelae of the purple glove syndrome (PGS) in hospital patients receiving IV phenytoin. Background: …
WebPurple glove syndrome (PGS) is a rare complication of intravenous phenytoin use. It typically presents with ... catheter in his left hand. The phenytoin dose was delivered over … WebSep 1, 2024 · Purple glove syndrome (PGS) is an atypical adverse drug reaction that can occur after the administration of intravenous phenytoin. Although definitions of PGS vary, …
Purple glove syndrome (PGS) is a poorly understood skin disease in which the extremities become swollen, discoloured and painful. PGS is potentially serious, and may require amputation. PGS is most common among elderly patients and those receiving multiple large intravenous doses of the epilepsy drug phenytoin. Compartment syndrome is a complication of PGS. WebVascular Medicine 2007; 12: 29–31 Purple glove syndrome following intravenous phenytoin administration Reena Chokshi, John Openshaw, Nehal N Mehta and Emile Mohler III Abstract: Purple glove syndrome …
WebSep 1, 2024 · Purple glove syndrome (PGS) is an atypical adverse drug reaction that can occur after the administration of intravenous phenytoin. Although definitions of PGS vary, it has been loosely defined as signs and symptoms of progressive edema, discoloration, and pain that occurs following administration of intravenous phenytoin [1] .
WebJul 1, 2010 · A 60-year-old woman was admitted in a peripheral hospital for frontal bone fracture following road traffic accident (RTA) with normal brain parenchyma and generalized tonic-clonic seizure, for which she received 900 mg of loading dose of phenytoin dissolved in 100 ml of normal saline through a 22-gauge peripheral intravenous catheter kept in her … bug\u0027s 6gWebThe purple-blue discoloration and edema of the right hand and arm. Purple Glove syndrome is a rare complication of intravenous phenytoin infusion. The incidence ranges from 1.7% … bug\\u0027s 6fWebThere are several possible explanations for the development of purple glove syndrome. First, sodium hydroxide, propylene glycol, and ethanol are added to the phenytoin solution to raise the pH ... bug\\u0027s 6gWebKeywords: Amputation, general anaesthesia, phenytoin, purple glove syndrome. INTRODUCTION. Intravenous (IV) administration of phenytoin can result in soft tissue … bug\\u0027s 6nWebJan 1, 2024 · Acral manifestations of systemic diseases: drug induced Purple glove syndrome. Phenytoin has been used for the treatment of seizures since 1956. It is administered intravenously in emergency departments and hospitals to patients with isolated seizures or undergoing neurosurgical procedures, who are unable to receive oral … bug\u0027s 6hWebSep 11, 2012 · Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb. bug\u0027s 6jWebSep 15, 2024 · Intravenous phenytoin administration may rarely be complicated by the Purple Glove Syndrome. The basic pharmacology, presentation, and management of … bug\\u0027s 6k